Archive for the 'Research' Category

Doctors find a more effective treatment for convergence insufficiency

Findings from a study conducted by optometrists from the Nova Southeastern University have concluded that a combination of in-office therapy and at-home treatment can be the most effective solution to treat a common childhood eye problem, convergence insufficiency. Children in this condition can not point their eyes together accurately. This causes eye strain. Patients see double. Traditional treatment of this condition has been home-based only. This study emphasizes that if a trained therapist provides office-based treatment along with at-home therapy, results will be better.

GPR91 receptor can be key to eye health

Researchers at the University of Montreal and St. Justine Hospital have identified a new receptor called GPR91 that can cure a number of eye diseases in diabetics, premature babies and the elderly by activating growth of blood vessels. The study is the first of its kind to show how ganglion cells that need oxygen to nourish produce blood vessels to feed themselves. Doctors have expressed their concern about the uncontrolled growth of blood vessels that can eventually cut the retina off the back of the eye causing vision loss. They are, now, working on various aspects of the study such as the receptor’s ability to drive the formation of blood networks and blocking GPR91 to stop tumor growth.

Turmeric prevents diabetic retinopathy: Research

Indian scientists, in a recently conducted research, have found that the turmeric spice (obtained from the rhizome of the Curcuma longa plant) can prove beneficial in the blockage of a biological pathway which leads to the progression of diabetic retinopathy, a complication that can cause blindness, if not treated at the right stage. A study showing that the incidence of diabetic retinopathy was much lower in Indians as compared to Europeans made the researchers curious about the ingredients of Indian diet that were helpful in preventing the disease. Curcumin’s anti-angiogenic effects against cancer, the scientists guessed, may also curb the growth of new blood vessels in the retina.

Study finds Takeda’s candesartan effective against diabetic retinopathy

Three recent studies conducted to examine the role of Takeda Pharmaceutical’s candesartan, the angiotensin receptor blocker (ARB) in the prevention and treatment of diabetic retinopathy have concluded that candesartan is one of the useful treatment options available for the disorder. The research found it to be the first pharmaceutical agent to have improved the patient’s condition in early retinopathy. Candesartan lowered the incidence of retinopathy in both type 1 diabetics (who had not developed it) and improved the condition in type 2 diabetes patients (who had it already).

Study: New age disposable lens prevents corneal infection

Australian researchers at the Moorfields Eye Hospital in London have conducted a study which reveals that the rate of corneal infection related to contact lens is 4.2 per 10,000 wearers per year. The scientists, in the first study of its kind, seek to describe the incidence of infection associated with the two new kinds of lenses introduced with the expectation of reducing the risk of infection — daily disposable soft lenses (launched in 1995), and silicone hydrogel lenses (launched in 1999). Planned replacement soft lens is better and safe for the eyes. The new age soft lens, Silicone hydrogel lens users who kept their lenses in overnight had the greatest disease incidence. But, proper use of daily disposable lenses made them the one with the lowest risk of a severe form of disorder as elimination of storage reduced the probability of contamination.

Research develops receptors to test for drugs for blindness

Researchers at the Oklahoma Health Sciences Center have developed the first ever genetic model of a microscopic part of the eye, the absence of which causes blindness. The study, aimed at knowing the effects of diabetes, focuses on the functioning of receptors work and the role of proteins and insulin in it. The doctors hope to find an effective treatment of diabetic retinopathy through the model. Various drugs and therapies will be tested on the model to find ways for enhancing the life of receptor cells and prevent blindness.

New contact lens delivers drug into eyes

Mark Byrne, a researcher at Auburn University, Alabama has claimed that he has developed a contact lens material that can prove to be helpful in getting medication into the eyes in adequate quantities. He has pointed out that the eye is adapted to keeping alien objects out. The contact-lens material developed by Byrne is capable of holding high concentration of medicines, releasing them slowly. The basis of the idea is to design the molecular structure of the lens material to emulate tissue-receptor sites within the body which are the targets of the drug. Byrne has established a company, OcuMedic, which will market the innovation. It has already been developing anti-fungal contact lenses to treat eye infections in horses.

Protein cure for macular degeneration, diabetic retinopathy

EyeResearchers at the University of Utah School of Medicine and other institutes have announced that age-related macular degeneration and diabetic retinopathy could be prevented or reversed by activating a protein, Robo4, in blood vessel cells through drugs. The research was conducted in mice models simulating age-related macular degeneration (AMD) and diabetic retinopathy. The protein acted by inhibiting abnormal blood vessel growth and preventing leakage by stabilizing blood vessels.

Photo by circo de invierno

Hope for adults suffering from lazy eye

American and Chinese researchers say that a new treatment for lazy eye has shown encouraging results in 20-year-old volunteers. The disease is also known as amblyopia and is considered to be irreversible after the age of eight years. The new method is called perceptual learning and uses training with simple visual tasks for vision improvement.

FAME study can continue without change

EyepSivida Limited has announced that the FAME™ (Fluocinolone Acetonide in Diabetic Macular Edema) Study can continue under the current protocol. The trial is studying the use of Medidur FA in diabetic macular edema (DME). The FAME™ study is being conducted on 956 patients in the U.S., Canada, Europe and India and it consists of two, duplicate, double-masked, randomized and multi-center trials.

Photo by R’eyes

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